ISSUES EDITED

2019

• 234. D’Alessandro A, Thomas KA, Gamboni F, Reisz JA, Spinella PC. Platelet storage temperature and metabolomics. Transfusion 2019; DOI: 10.1111/trf.15651

• 233. Janssen WJ, Danhorn T, Harris C, Mould KJ, Lee FFY, Hedin BR, D’Alessandro A, Leach SM, Alper S. Inflammation-induced alternative pre-mRNA splicing in mouse alveolar macrophages. G3 2019; DOI: 10.1534/g3.119.400935

• 232. Abraham A, Esquer H, Zhou Q, Tomlinson N, Hamill B, Abbott J, Li L, Pike L, Rinaldetti S, Gomez J, Shaack J, Nemkov T, D’Alessandro A, Hansen K, Messersmith W, LaBarbera D. Drug Design Targeting TCF-Driven Epithelial-Mesenchymal Transition as a Therapeutic Strategy for Colorectal Cancer. J Med Chem 2019; 62 (22), 10182-10203

• 231. Hunter S, Hoffman CM, D’Alessandro A, Noonana K, Wyrwaa Am Freedman R, Law AJ. Prenatal Inflammation and Development of Cerebral Inhibition and Infant Behaviors Associated with Later Mental Illness. Psych J 2019; doi: 10.1007/s11920-014-0546-9

• 230. Johnson LC, Parker K, Aguirre BF, Nemkov T, D’Alessandro A, Johnson SA, Seals DR, Martens CR. The plasma metabolome as a predictor of biological aging in humans. GeroScience 2019; DOI: 10.1007/s11357-019-00123-w

• 229. Stefanoni D, Champagne DP, Nemkov T, Spitalnik SL, Buehler P, D’Alessandro A. Red Blood Cell metabolism in macaques and humans: comparative biology of blood storage. Haematologica 2019; DOI: 10.3324/haematol.2019.229930

• 228. Sonn BJ, Saben JL, Shelton S, Flaten HK, D’Alessandro A, Monte A. Clinical and Metabolic markers predicting efficacy of lisinopril therapy. Metabolomics 2019; DOI: 10.1007/s11306-019-1601-7

• 227. Powers R, Sullivan K, Culp-Hill R, Ludwig M, Smith KP, Waugh K, Minter R, Tuttle KD, Rachubinski A, Granrath RE, Wilkerson RE, D’Alessandro A, Espinosa J, Costello J. Trisomy 21 disrupts tryptophan catabolism toward production of neurotoxic metabolites via the interferon-inducible kynurenine pathway. Nature Communications 2019;

• 226.Chang EI, Wesolowski SR, Gilje EA, Baker PR, Reisz JA, D’Alessandro A, Hay WW, Rozance PJ, Brown LD. Hindlimb (skeletal muscle) amino acid uptake is lower and alanine production greater in late gestation intrauterine growth restricted fetal sheep. Paediatrics 2019; 317 (5), R615-R629

• 225.Nohara K, Nemkov T, D’Alessandro A, Yoo SH, Chen Z. Coordinate regulation of cholesterol and bile acid metabolism by the clock modifier Nobiletin in metabolically challenged old mice. Int J Mol Sci 2019; 20(17): 4281.

• 224. Moore HB, Culp-Hill R, Reisz JA, Lawson PJ, Sauaia A, Schulick RD, Del Chiaro M, Nydam T, Moore EE, Hansen KC, D’Alessandro A. The metabolic time line of pancreatic cancer: opportunities to improve early detection of adenocarcinoma. Annals of Surgery 2019; 218 (6), 1206-1212

• 223. La Carpia F, Wojczyk B, Annavajhala M, Rebbaa A, Shabro A, Culp-Hill R, D’Alessandro A, Freedberg D, Uhlemann AC, Hod EA. Transfusional iron overload and intravenous iron injections modify the mouse gut microbiome similarly to dietary iron. Biomolecules and Biofilms 2019;

• 222. Kazunari J, Nemkov T, D’Alessandro A, Zheng C. The clock-enhancing agent Nobiletin promotes healthy aging via optimization of skeletal muscle mitochondrial respiratory complexes. Nature Communications 2019;

• 221. Adebyi M, Zhao Z, Ye Y, Manalo J, Hong Y, Lee CC, Xian W, McKeon F, Hill R, D’Alessandro A, Kellems RE, Yoo SH, Han L, Xia Y. The beneficial role of elevated circadian Period 2 in sickle cell disease mice. FASEB J 2019; doi: 10.1096/fj.201900246RR.

• 220. Davizon-Castillo P, McMahon B, Aguila S, Bark D, Ashworth K, Campbell RA, Montenont E, Nemkov T, D’Alessandro A, Clendenen N, Shih L, Sanders NA, Higa K, Cox A, Padilla-Romo Z, Hernandez G, Wartchow E, Pietras E, Trahan GD, Jones K, DeGregori J, Rondina MT, Di Paola J. TNF-a driven inflammation and mitochondrial dysfunction define the platelet hyperreactivity of aging. Blood 2019; 134 (9), 727-740

• 219. D’Alessandro A, Hansen KC, Eisenmesser EZ, Zimring JC. Protect, Repair, Destroy or Sacrifice: could inter-donor variability in the capacity to generate and cope with oxidant stress drive the heterogeneity in progression and severity of the storage lesion across blood donors? Blood Transfusion 2019; 17 (4), 281-288

• 218. Gehrke S, Shah N, Gamboni F, Gray A, Landrigan M, Welsby I, D’Alessandro A. Metabolic impact of exchange transfusion with rejuvenated red blood cells in sickle cell patients. Transfusion 2019; 59 (10), 3102-3112

• 217. Morrison EJ, Champagne D, Dzieciatkowska M, Nemkov T, Zimring JC, Hansen KC, Guan F, Huffman DM, Santambrogio L, D’Alessandro A. The impact of aging and parabiosis on mouse red blood cell metabolism. Nutrients 2019; doi: 10.3390/nu11061337 

• 216. D’Alessandro A, Liumbruno GM. Personalized Transfusion Medicine. Blood Transfusion 2019; 17(4): 255–257.

• 215.Hoffman CM, Hunter S, D’Alessandro A, Noonan K, Freedman R. Choline Mitigation of Marijuana’s Effects on the Fetal Brain and Child Behavior. Psychological Medicine 2019; DOI: 10.1017/S003329171900179X
  •    214. Williams AT, Jani V, Nemkov T, Lucas A, Yoshida T, Dunham A, D’Alessandro A, Cabrales P. Anaerobically versus conventionally stored blood transfusion after trauma. Shock 2019; DOI: 10.1097/SHK.0000000000001386
  •    213. Howie HL, Hay A, de Wolski K, Waterman H, Fu X, Culp-Hill R, D’Alessandro A, Thomson P, Zimring JC. Genetic Variation of Steap3 Expression is Responsible for Altered Oxidative Damage and Post-Storage RBC Transfusion Biology in a Murine Model. Blood Advances 2019; 3(15):2272-2285.
  •    212. Jones CL, Stevens BM, D’Alessandro A, Culp-Hill R, Reisz JA, Khan N, Agnello G, Rowlinson S, DeGregori J, Pollyea DA, Jordan CT. Cysteine depletion targets leukemia stem cells through inhibition of electron transport complex II. Blood 2019; doi: 10.1182/blood.2019898114.
  •    211. Gaikwad H, Wang G, Smith WJ, Alexander KL, D’Alessandro A, Zhang W, Purev E, Simberg D. Clickable Methyltetrazine-Indocarbocyanine Lipids: A Multicolor Tool Kit for Efficient Modifications of Cell Membranes. Bioconjug Chem. 2019; doi: 10.1021/acs.bioconjchem.9b00202.
  •    210. Nechiporuk T, Kurtz SE, Nikolova O, Liu T, Jones CL, D’Alessandro A, Culp-Hill R, d’Alemeida A, Rosenberg M, Tognon C, Danilov AV, Druker BJ, McWeeney SK, Tyner JW. A genome-wide CRISPR screen on AML cells reveals TP53 apoptotic network is a primary mediator of resistance to BCL2 inhibition. Cancer Discovery 2019; doi: 10.1158/2159-8290.CD-19-0125.
  •    209. Schmitt L, Henderson R, Barrett A, Darula Z, Issaian A, D’Alessandro A, Chalkley R, Clendenen N, Hansen KC. Molecular Mapping of FXIIIa Cross-links in fibrin clots using cross-linking-Mass Spectrometry. JBC 2019; doi: 10.1074/jbc.AC119.007981.
  •    208.Adane B, Ye H, Khan N, Pei S, Minhajuddin M, Stevens BM, Jones CL, D’Alessandro A, Reisz JA, Zaberezhnyy V, Gasparetto M, Ho TC, Kelly KK, Myers JR, Ashton JM, Siegenthaler J, Kume T, Campbell EL, Pollyea DA, Becker MW, Jordan CT. The Hematopoietic Oxidase NOX2 Regulates Self-Renewal of Leukemic Stem Cells. Cell Rep. 2019 Apr 2;27(1):238-254.e6.
  •    207. Francis RO, Mahajan S, Rapido F, La Carpia F, Soffing M, Divgi C, Yeh R, Mintz A, Leslie L, Agrest I, Karafin M, Ginzburg Y, Kessler D, Shaz BH, Spitalnik SL, Schwartz J, Fu X, Amireault P, Buffet P, Zimring JC, D’Alessandro A, Hod EA. Re-examination of the chromium-51-labeled post-transfusion red blood cell recovery method. Transfusion 2019; doi: 10.1111/trf.15310.
  •    206. F Freedman R, Hunter SK, Law AJ, Wagner BD, D'Alessandro A, Christians U, Noonan K, Wyrwa A, Hoffman MC. Higher Gestational Choline Levels in Maternal Infection Are Protective for Infant Brain Development. J Pediatr. 2019;208:198-206.e2.
  •    205. Henriksen HH, McGarrity S, Siguordottir RS, Nemkov T, D’Alessandro A, Stensballe J, Wade CE, Rolfsson O, Johansson PI. Metabolic systems analysis of shock induced endotheliopathy (SHINE) in Trauma – A new paradigm. Annals of Surgery 2019; in press
  •    204. Gehrke S, Rice S, Stefanoni D, Wilkerson R, Nemkov T, Reisz JA, Hansen KC, Lucas A, Cabrales P, Drew K, D’Alessandro A. Red Blood Cell metabolic responses to torpor and arousal in the hibernator arctic ground squirrel. J Prot Res 2019; 18(4):1827-1841.
  •    203. Gregory MA, Nemkov T, Park HJ, Zaberezhnvv V, Gehrke S, Adane B, Jordan CT, Hansen KC, D’Alessandro A, DeGregori J. Targeting glutamine metabolism and redox  state for leukemia therapy. Clin Cancer Res. 2019; pii: clincanres.3223.2018. doi: 10.1158/1078-0432.CCR-18-3223.
  •    202. D’Alessandro A, Reisz JA, Zhang Y, Gehrke S, Alexander K, Kanias T, Triulzi D, Donadee C, Barge S, Badlam J, Jain S, Belanger AM, Risbano MG, Gladwin MT. Effects of aged stored autologous red blood cells on human plasma metabolism. Blood Advances 2019; 3(6):884-896.
  •    201. Pham-Danis C, Gehrke S, Danis E, Rohzok A, Daniels M, Gao D, Collins C, Di Paola J, D’Alessandro A, DeGregori J. EGFR inhibition promotes dependency on the urea cycle in EGFR mutant NSCLC. Mol Cancer Res 2018; doi: 10.1158/1541-7786.MCR-18-1068.
  •    200.D’Alessandro A, Zimring JC, Busch M. Chronological storage age and metabolic age of stored red blood cells: are they the same? Transfusion. 2019;59(5):1620-1623.
  •    199. D’Alessandro A. From omics technologies to personalized transfusion medicine. Exp Rev Prot 2019;16(3):215-225.
  •    198. Clendenen N, Clendenen N, Nunns GR, Moore EE, Gonzalez E, Chapman M, Reisz JA, Peltz E, Fragoso M, Nemkov T, Wither MJ, Sauaia A, Silliman CC, Hansen K, Banerjee A, D'Alessandro A, Moore HB. Selective organ ischaemia/reperfusion identifies liver as the key driver of the post-injury plasma metabolome derangements. Blood Transfus. 2018; doi: 10.2450/2018.0188-18.
  •    197. Rogers SC, Dosier LB, McMahon TJ, Zhu H, Timm D, Zhang H, Herbert J, Atallah J, Palmer G, Cook A, Ernst M, Prakesh H, Terng M, Towfighi P, Doctor R, Said A, Joens M, Fitzpatrick J, Hanna G, Lin X, Reisz JA, Nemkov T, D’Alessandro A, Doctor A. Red Blood Cell Phenotype Fidelity following Glycerol Cryopreservation Optimized for Research Purposes. PLoS One. 2018;13(12):e0209201. 
  •    196. Moore HB, D’Alessandro A, Moore EE, Wither M, Lawson P, Hansen K, Kam I, Wachs ME, Silliman CC, Banerjee A, Nydam T. Increase in post-reperfusion sensitivity to tissue plasminogen activator-mediated fibrinolysis during liver transplantation is associated with abnormal metabolic changes and increased blood product. Blood Transfus. 2019; doi: 10.2450/2019.0205-18.
  •    195. Hoffman C, Olincy A, D’Alessandro A, Reisz JA, Hansen KC, Hunter SK, Freedman R, Ross RG. Effects of phosphatidylcholine and betaine supplements on women's serum choline. J Nutr Int Metabolism 2019;
  •    194. Yoshida T, Prudent M, D’Alessandro A. Red blood cell storage lesion: causes and potential clinical consequences. Blood Transfus. 2019;17(1):27-52. *corresponding author
  •    193. Lana A*, Alexander K, Castagna A, D'Alessandro A, Morandini F, Pizzolo F, Zorzi F, Mulatero P, Zolla L, Olivieri O. Urinary metabolic signature of primary aldosteronism: gender and subtype specific alterations. Proteomics Clinical Applicaitons 2019; doi: 10.1002/prca.201800049.*shared first authorship
  •    192.    Moon SH, Huang CH, Houlihan SL, Regunath K, Freed-Pastor WA, Morris IV JP, Tschaharganeh DF, Kastenhuber ER, Barsotti AM, Culp‐Hill R, Xue W, Ho YJ, Baslan T, Li X, Mayle A, de Stanchina E, Zender L, Tong DR, D’Alessandro A, Lowe SW, Prives C. p53 Represses the Mevalonate Pathway to Mediate Tumor Suppression. Cell 2019; 176(3):564-580.e19.
  •    191.    Fox B, Hyo-Wook G, Griffin B, Jovanovich A, Soranno DE, Gist K, Haines JR, Wither M, D’Alessandro A, Altmann C, Faubel S. Metabolomics assessment reveals oxidative stress and altered energy production in the heart after ischemic acute kidney injury in mice. Kidney International 2019; 95(3):590-610.
  •    190.    Soderborg TK, Mulligan CE, Clark SE, Babcock L, Janssen RC, Lemas DL, Johnson LK, Frank DN, Weir T, Baarbour LA, Hernandez TL, Kuhn KA, D’Alessandro A, El Kasmi KC, Friedman JE. The Gut Microbiome in Infants of Obese Mothers Increases Hepatic Inflammation and Susceptibility to Obesity and NAFLD in Germ-free Mice. Nature Communications 2019; accepted – waiting for doi
  •    189.    Sheridan R, Fong N, D’Alessandro A, Bentley D. Widespread Backtracking by RNA Pol II Is a Major Effector of Gene Activation, 5' Pause Release, Termination, and Transcription Elongation Rate. Molecular Cell; 2019; Mol Cell. 2019 Jan 3;73(1):107-118.e4.
  •    188.    Nemkov T, D’Alessandro A, Reisz JA. Metabolic underpinnings of leukemia pathology and treatment. Cancer Reports 2019; invited review

2018

• 187. Soderborg TK, Clark SE, Mulligan CE, Janssen RC, Babcock L, Ir D, Lemas DJ, Johnson LK, Weir T, Lenz LL, Frank DN, Hernandez TL, Kuhn KA, D'Alessandro A, Barbour LA, El Kasmi KC, Friedman JE. The gut microbiota in infants of obese mothers increases inflammation and susceptibility to NAFLD. Nat Commun. 2018 Oct  26;9(1):4462. 

• 186. Wesolowski SR, Mulligan CM, Janssen RC, Baker PR 2nd, Bergman BC, D'Alessandro A, Nemkov T, Maclean KN, Jiang H, Dean TA, Takahashi DL, Kievit P, McCurdy CE, Aagaard KM, Friedman JE. Switching obese mothers to a healthy diet improves fetal hypoxemia, hepatic metabolites, and lipotoxicity in non-human primates. Mol Metab. 2018 Dec;18:25-41.

• 185. Nemkov T, Reisz JA, Xia Y, Zimring JC, D'Alessandro A. Red blood cells as an organ? How deep omics characterization of the most abundant cell in the human body highlights other systemic metabolic functions beyond oxygen transport. Expert Rev Proteomics. 2018 Nov;15(11):855-864.

• 184. Reisz JA, Nemkov T, Dzieciatkowska M, Culp-Hill R, Stefanoni D, Hill RC, Yoshida T, Dunham A, Kanias T, Gladwin MT, Kleinman S, Dumont LJ, Busch M, Eisenmesser EZ, Zimring JC, Hansen KC, D’Alessandro A. Methylation of aspartates and deamidated asparagines as a function of blood bank storage and oxidative stress in human red blood cells. Transfusion. 2018 Oct 12. doi: 10.1111/trf.14936. 

• 183. D’Alessandro A, Culp-Hill R, Reisz JA, Anderson M,  Fu X, Nemkov T, Gehrke S, Zheng C, Kanias T, Guo J, Page G, Gladwin M, Kleinman S, Lanteri M, Stone M, Busch M, Zimring JC. Heterogeneity of blood processing and storage additives in different centers impacts stored Red Blood Cell metabolism as much as storage time: lessons from REDS III – Omics. Transfusion 2018; waiting for doi

• 182. Jones CL, Stevens BM, D’Alessandro A, Reisz JA, Culp-Hill R, Nemkov T, Pei S, Khan N, Smith C, DeGregori J, Pollyea D, Jordan CT. Venetoclax + Azacytidine Disrupts Amino Acid Metabolism and Targets Leukemia Stem Cells. Nat Med. 2018 Nov 12. doi: 10.1038/s41591-018-0233-1.

• 181. Pollyea DA, Stevens BM, Jones CL, Winters A, Pei S, Minhajuddin M, D’Alessandro A, Culp-Hill R, Riemondy KA, Gillen AE, Hesselberth JR, Abbot D, Schatz D, Gutman JA, Purev E, Smith C, Jordan CT. The BCL-2 Inhibitor Venetoclax in Combination with Azacitidine Disrupts Energy Metabolism and Targets Leukemia Stem Cells in Acute Myeloid Leukemia Patients. Cancer Cell. 2018 Nov 12;34(5):724-740.e4. doi: 10.1016/j.ccell.2018.10.005.

• 180.Rogers TJ, Green LI, Christenson JL, O’Neill K, Gordon M, Nemkov T, D’Alessandro A, Degala G, Shin J, Tan AC, Labmbert J, Torko K, Richer JK. microrna-200c regulates tryptophan catabolism, pd-l1, and other pathways of immune evasion in breast cancer. Mol Cancer Res. 2018 Sep 13. doi: 10.1158/1541-7786.MCR-18-0246.

• 179. Culp-Hill R, Srinivassan J, Gehrke S, Ansari A, Shah N, Welsby I, D’Alessandro A. Effects of red blood cell transfusion on sickle cell disease recipient plasma and erythrocyte metabolism. Transfusion. 2018 Sep 28. doi: 10.1111/trf.14931.

• 178. Stevens BM, Khan N, D’Alessandro A, Nemkov T, Winters A, Zhang W, Pollyea DA, Jordan CT. Characterization and Targeting of Emergent Acute Myeloid Leukemia (AML) Stem Cells in Patients with Myelodysplastic Syndromes (MDS). Nat Commun. 2018 Sep 12;9(1):3694

• 177. Greene L, Bruno TC, Christenson JL, D’Alessandro A, Culp-Hill R, Torkko K, Borges VF, Slansky JE, Richer JK. : A role for tryptophan 2,3-dioxygenase in CD8 T cell suppression and evidence of tryptophan catabolism in breast cancer patient plasma. Mol Cancer Therapeutics 2018; Accepted – waiting for doi

• 176. Klarquist JS, Chitrakar A, Pennock NA, Kilgore AM, Bla in T, Jiang L, Sun J, Hunter CA, D’Alessandro A, Keld RM. Vaccine-elicited T cell responses utilize IL-27 and IL-15 to support clonal expansion independent of aerobic glycolysis. Science Immunology 2018; Vol. 3, Issue 27, eaas9822; DOI: 10.1126/sciimmunol.aas9822

• 175. Karafin M, Fu X, D’Alessandro A, Thomas T, Hod E, Zimring JC, Field J, Francis RO. The Clinical Impact of Glucose-6-Phosphate Dehydrogenase Deficiency in Patients with Sickle Cell Disease. Curr Opin Hematol 2018; Accepted – waiting for doi

• 174. Catala A, Culp-Hill R, Nemkov T, D’Alessandro A. Quantitative metabolomics comparison of traditional blood draws and TAP capillary blood collection. Metabolomics 2018;

• 173. Paukovich N, Xue M, Elder JR, Redzic JS, Blue AS, Pike H, Miller BG, Pitts T, Pollock DD, Hansen KC, D’Alessandro A, Eisenmesser EZ. Biliverdin reductase B dynamics are coupled to coenzyme binding. J Mol Biol. 2018 Sep 14;430(18 Pt B):3234-3250.

• 172. Clendenen N, D’Alessandro A. High Throughput Metabolomics in Clinical Studies: application to remote ischemic preconditioning. Curr Topics In Medicinal Chem 2018; Accepted – waiting for doi

• 171. Zhang C, D’Alessandro A, Wellendorf A, Whitsett J, Perentesis J, Kumarov K, Stegmaier K, Grimes HL, Cancelas JA. KLF5 tumor suppressor activity of Ph+ B-cell acute lymphoblastic leukemia depends on activation of an anti-oxidant transcriptional program. Oncotarget 2018; Accepted waiting for doi

• 170. Faulds KJ, Egleston J, Sedivy LJ,Graimella S, Kozlowski H, D’Alessandro A, Hansen KC, Balsbaugh JL, Phiel CJ. A Role For Glycogen Synthase Kinase-3 (Gsk-3) in the Regulation of mRNA Methylation in Mouse Embryonic Stem Cells. Biochemistry 2018; J Biol Chem. 2018 Jul 6;293(27):10731-10743.

• 169. Graham B, Kumar R, Mickael C, Kassa B, Koyanagi D, Zhang L, Perez M, Hernandez-Saavedra D, Valencia C, Dixon K, Loomis Z, Nemkov T, Irwin D, D’Alessandro A, Stenmark K, Tuder R. Vascular adaptation of the right ventricle in severe experimental pulmonary hypertension. Am J Respir Cell Mol Biol. 2018 May 31. doi: 10.1165/rcmb.2018-0095OC.

• 168. Zhang Y, Christian BE, Lee JH, Paull TT, Schroeder EA, Gehrke S, D’Alessandro A, Shadel G. Mitochondrial redox signaling by ATM regulates cellular antioxidant capacity. Sci Signal. 2018 Jul 10;11(538). 

• 167. El Kasmi KC, Vue PM, Anderson AL, Devereaux MW, Ghosh S, Balasubramaniyan N, Fillon SA, Dahrenmoeller C, Allawzi A, Woods C, McKenna S, Wright CJ, Johnson L, D’Alessandro A, Reisz JA, Grayck E, Suchy FJ, Sokol RJ. Macrophage-derived IL-1b/NFkB signaling mediates Parenteral Nutrition Associated Cholestasis. Nature Communications 2018; 9(1):1393. doi: 10.1038/s41467-018-03764-1

• 166. D’Alessandro A, Reisz JA, Culp-Hill R, De Korte D, van Bruggen R. The (non-)commutative property of addition to red blood cell storage formulations: effects of alkaline additives and guanosine/gluconate. Transfusion 2018; doi: 10.1111/trf.14620.

• 165. Gehrke S, Srivanasan J, Culp-Hill R, Reisz JA, Ansari A, Alan Gray, Matthew Landrigan, Welsby I, D’Alessandro A. Cold bedside rejuvenation as an alternative rejuvenation practice. Transfusion. 2018. doi: 10.1111/trf.14623. *corresponding author

• 164. Banerjee A, Silliman CC, Moore EE, Dzieciatskowa M, Kelher M, Sauaia A, Jones K, Chapman MP, Gonzalez E, Moore HB, D'Alessandro A, Peltz E, Huebner BE, Einerson P, Chandler J, Ghasabayan A, Hansen K. Systemic Hyperfibrinolysis after Trauma: A Pilot study of Targeted Proteomic Analysis of Superposed Mechanisms in Patient Plasma. J Trauma Acute Care Surg. 2018 Mar 16. doi: 10.1097/TA.0000000000001878.

• 163. Chicco AJ, Le CH, Gnaiger E, Dreyer HC, Muyskens JB, D'Alessandro A, Nemkov T, Hocker AD, Prenni JE, Wolfe LM, Sindt NM, Lovering AT, Subudhi AW, Roach RC. Adaptive remodeling of skeletal muscle energy metabolism in high-altitude hypoxia: Lessons from AltitudeOmics. J Biol Chem. 2018 Mar 14. pii: jbc.RA117.000470.

• 162. Reisz JA, Barrett AS, Nemkov T, Hansen KC, D'Alessandro A. When nature's robots go rogue: exploring protein homeostasis dysfunction and the implications for understanding human aging disease pathologies. Expert Rev Proteomics. 2018 Mar 21:1-17. doi: 10.1080/14789450.2018.1453362.

• 161. Marchetti C, Swartzwelter B, Gamboni F, Neff CP, Richter K, Azam T, Carta S, Tengesdal I, Nemkov T, D'Alessandro A, Henry C, Jones GS, Goodrich SA, St Laurent JP, Jones TM, Scribner CL, Barrow RB, Altman RD, Skouras DB, Gattorno M, Grau V, Janciauskiene S, Rubartelli A, Joosten LAB, Dinarello CA. OLT1177, a β-sulfonyl nitrile compound, safe in humans, inhibits the NLRP3 inflammasome and reverses the metabolic cost of inflammation. Proc Natl Acad Sci U S A. 2018 Feb 13;115(7):E1530-E1539.

• 160. Friedman JE, Dobrinskikh E, Alfonso-Garcia A, Fast A, Janssen RC, Soderborg TK, Anderson AL, Reisz JA, D'Alessandro A, Frank DN, Robertson CE, de la Houssaye BA, Johnson LK, Orlicky DJ, Wang XX, Levi M, Potma EO, El Kasmi KC, Jonscher KR. Pyrroloquinoline quinone prevents developmental programming of microbial dysbiosis and macrophage polarization to attenuate liver fibrosis in offspring of obese mice. Hepatol Commun. 2018;2(3):313-328.

• 159. Perreault L, Newsom S, Strauss A, Kerege A, Kahn T, Harrison K, Snell-Bergeon J, Nemkov T, D’Alessandro A, Jackman M, MacLean P, Bergman BC. Intracellular Localization of Diacylglycerols and Sphingolipids influence Insulin Sensitivity and Mitochondrial Function in Human Skeletal Muscle. JCI Insight 2018;3(3). pii: 96805. doi: 10.1172/jci.insight.96805.

• 158. Reisz JA, Tzounaka VL, Nemkov T, Voulgaridou AI, Papassideri IS, Kriebardis AG, D’Alessandro A, Antonelou MH. Metabolic linkage and correlations to storage capacity in erythrocytes from glucose 6-phosphate dehydrogenase deficient donors. Frontiers in Medicine 2018 Jan 11;

• 157. Vostal JG, Buehler PW, Gelderman MP, Alayash AI, Doctor A, Zimring JC, Glynn S, Hess JR, Klein H, Acker J, Spinella P, D’Alessandro A, Palsson B, Raife TJ, Busch MP, McMahon T, Intaglietta M, Swartz HM, Dubick MA, Cardin S, Patel RP, Natanson C, Weisel JW, Muszynski JA, Norris PJ, Ness PM. Proceedings of the Food and Drug Administration’s Public Workshop on New Red Blood Cell Product Regulatory Science 2016; Transfusion. 2018. doi: 10.1111/trf.14435.