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Balance Your Folate Or The Yin And Yang Of Folate In Hematopoiesis

Congratulations to Curtis Henry (Emory University, Atlanta), our friend and mentor James DeGregori and our own Travis for a well-deserved research highlight appeared in Haematologica today. This commentary provides an overview of our recent collaborative paper with the DeGregori lab, where we showed that both low or high levels of dietary folate compromise hematopoiesis in mice, and affect the B-cell progenitor compartment in particular. "Given that there are substantial fractions of the world population at risk for either excessive (via fortified diets) or very low folate intake," Dr. Hartmut Geiger comments "this study might contribute to novel public policy recommendations on the level of folate intake, specifically in the context of fortified diets."

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